Ciprofloxacin 0.3% and Dexamethasone 0.1% Ear Drops OTIC Suspension, Sterile 15 mL (RX)Ciprofloxacin 0. 3% and Dexamethasone 0. 1% Ear Drops is a combination medication used to treat certain types of ear infections, including otitis externa (outer ear infections) and otitis media with tympanostomy tubes in place (middle ear infections with small tubes inserted for drainage). Ciprofloxacin is an antibiotic that kills bacteria causing the infection, while dexamethasone is a steroid that reduces inflammation and swelling in the ear.